St. Charles (©D. Lancaster)
St. Charles was Missouri’s first capital in 1821, and the entire National Register Historic District on the banks of the Missouri River has been preserved and restored. Historic South Main Street is lined with more than 125 specialty shops, restaurants, museums and attractions, including Missouri’s First State Capitol State Historic Site, Foundry Art Centre and the Lewis & Clark Boathouse and Nature Center. I-70 west across the Missouri River, N. Fifth Street exit, right on Boone’s Lick Road to the riverfront.